PI3 Kinase [p110α (E545K)/p85α], His-Tag Recombinant 40644 from BPS Bioscience, Inc.

Description

Complex of recombinant full-length human p110α (GenBank Accession No. NM_006218) with E545K mutation and N-terminal His-Tag, and recombinant full length, human p85α (GenBank Accession No. NM_181523), no tag. Co-expressed in Sf9 cells in a Baculovirus expression system. p110α (E545K) MW=111 kDa, p85α MW=86 kDa

Product Specs
ItemPI3 Kinase [p110α (E545K)/p85α], His-Tag Recombinant
CompanyBPS Bioscience, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number40644
Quantity10 µg
Conjugate/Tagp110α: N-terminal His-Tag, p85α: No Tag
Format50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol
Molecular Weightp110α (E545K): 111 kDa, p85α: 86 kDa
SpeciesHuman
Domain/Region/Terminusfull length
NCBI Full Gene NameCD33 molecule, phosphoinositide-3-kinase regulatory subunit 1, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
NCBI Gene AliasesAGM7, CLOVE, MCMTC, CLAPO, p67, PI3K, SIGLEC-3, CWS5, p85-ALPHA, MCM, p85, IMD36, MCAP, p110-alpha, GRB1, PI3K-alpha, SIGLEC3
TypeProtein
Source/Expression SystemSf9 cells
insect
ApplicationsUseful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling